IM-93
IM-93 inhibits ferroptosis and NETosis with an IC50 of 0.45 µM for cell death inhibition[1].
Product Specifications
CAS Number
[1173657-73-2]
UNSPSC
12352005
Target
Ferroptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/im-93.html
Purity
99.00
Solubility
DMSO : 20 mg/mL (ultrasonic; warming)
Smiles
O=C(C(NCCCN(C)C)=C1C2=CN(C)C3=C2C=CC=C3)N(C(C)C)C1=O
Molecular Formula
C21H28N4O2
Molecular Weight
368.47
References & Citations
[1]Dodo K, et al. Development of a Water-Soluble Indolylmaleimide Derivative IM-93 Showing Dual Inhibition of Ferroptosis and NETosis. ACS Med Chem Lett. 2019;10 (9) :1272-1278. Published 2019 Jul 30.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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