Palvanil
Palvanil is a Capsaicin (HY-10448) analogue, shows strong desensitizing capability against the TRPV1 receptor. Palvanil shows anti-nociceptive and anti-inflammation effects[1][2].
Product Specifications
CAS Number
[69693-13-6]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
TRP Channel
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/palvanil.html
Purity
98.01
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
CCCCCCCCCCCCCCCC(NCC1=CC=C(O)C(OC)=C1)=O
Molecular Formula
C24H41NO3
Molecular Weight
391.59
Precautions
H302, H315, H319
References & Citations
[1]Luciano De Petrocellis, et al. N-palmitoyl-vanillamide (palvanil) is a non-pungent analogue of capsaicin with stronger desensitizing capability against the TRPV1 receptor and anti-hyperalgesic activity. Pharmacol Res. 2011 Apr;63 (4) :294-9.|[2]Livio Luongo, et al. Palvanil, a non-pungent capsaicin analogue, inhibits inflammatory and neuropathic pain with little effects on bronchopulmonary function and body temperature. Pharmacol Res. 2012 Sep;66 (3) :243-50.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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