Fusarochromanone
Product Specifications
UNSPSC Description
Fusarochromanone (FC-101) is a fungal metabolite with potent anti-angiogenic and anti-cancer activity[1]. Fusarochromanone-activated JNK pathway is attributed to induction of reactive oxygen species (ROS)[2].
Target Antigen
Reactive Oxygen Species
Type
Natural Products
Related Pathways
Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/fusarochromanone.html
Solubility
10 mM in DMSO
Smiles
O=C1CC(C)(C)OC2=CC=C(C(C[C@@H](N)CO)=O)C(N)=C12
Molecular Weight
292.33
References & Citations
[1]Elahe Mahdavian, et al.Biological activities of fusarochromanone: a potent anti-cancer agent. BMC Res Notes. 2014 Sep 3;7:601.|[2]Ying Gu, et al.Fusarochromanone-induced reactive oxygen species results in activation of JNK cascade and cell death by inhibiting protein phosphatases 2A and 5. Oncotarget. 2015 Dec 8;6(39):42322-33.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-136901/Fusarochromanone-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-136901/
Clinical Information
No Development Reported
CAS Number
802915-53-3
Curated Selection
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