Resolvin D3

Resolvin D3 (RvD3) is a docosahexaenoic acid (DHA) derived mediator. Resolvin D3 is dysregulated in arthritis and reduces arthritic inflammation[1][2].

Product Specifications

CAS Number

[916888-47-6]

Product Name Alternative

RvD3

UNSPSC

12352211

Hazard Statement

H225-H319

Target

AMPK; Autophagy

Type

Reference compound

Related Pathways

Autophagy; Epigenetics; PI3K/Akt/mTOR

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/resolvin-d3.html

Concentration

265.6 μM * 250 μL in Ethanol

Purity

95.0

Solubility

10 mM in DMSO

Smiles

CC/C=C\C[C@H](O)/C=C/C=C\C[C@@H](O)/C=C/C=C/C=C\[C@@H](O)CCC(O)=O

Molecular Formula

C22H32O5

Molecular Weight

376.49

Precautions

P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P370+P378-P403+P235-P501

References & Citations

[1]Hildur H Arnardottir, et al. Resolvin D3 Is Dysregulated in Arthritis and Reduces Arthritic Inflammation. J Immunol. 2016 Sep 15;197 (6) :2362-8.|[2]Jennifer K Colby, et al. Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Protective for Injured Epithelia. Am J Pathol. 2016 Jul;186 (7) :1801-1813.