IKK-IN-3
Product Specifications
UNSPSC Description
IKK-IN-3 is a potent and selective IkappaB kinase 2 (IKK2 or IKKβ) inhibitor, with IC50s of 19 and 400 nM for IKK2 and IKK1 (or IKKα), respectively[1].
Target Antigen
IKK
Type
Reference compound
Related Pathways
NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ikk-in-3.html
Solubility
10 mM in DMSO
Smiles
NCCNC1=NC(C=C(C2=CC=CC=C2)S3)=C3N4C1=NC=C4C
Molecular Weight
323.42
References & Citations
[1]Kempson J , et al. Novel tricyclic inhibitors of IkappaB kinase. J Med Chem. 2009;52(7):1994‐2005.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-136392/IKK-IN-3-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-136392/
Clinical Information
No Development Reported
CAS Number
615528-53-5
Curated Selection
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