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Holomycin

Holomycin is a secondary metabolite of the dithiolopyrrolone class. Holomycin also is a broad spectrum antibiotic. Holomycin has antitumor activity and can act in vivo on RNA synthesis[1].

Product Specifications

CAS Number

[488-04-0]

UNSPSC

12352005

Target

Antibiotic; DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Anti-infection; Cell Cycle/DNA Damage

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/holomycin.html

Purity

95.09

Solubility

10 mM in DMSO

Smiles

CC(NC1=C2C(NC1=O)=CSS2)=O

Molecular Formula

C7H6N2O2S2

Molecular Weight

214.26

References & Citations

[1]Paloma Liras, et al. Holomycin, a dithiolopyrrolone compound produced by Streptomyces clavuligerus. Appl Microbiol Biotechnol. 2014 Feb;98 (3) :1023-30.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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