2'-Ethyl Simvastatin
2'-Ethyl Simvastatin (compound 6) is a Mevinolin analog, with HMG-CoA reductase inhibition[1].
Product Specifications
CAS Number
[79902-42-4]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
HMG-CoA Reductase (HMGCR)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/2-ethyl-simvastatin.html
Solubility
10 mM in DMSO
Smiles
CC(C)C(O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(O3)=O)[C@@]12[H])=O
Molecular Formula
C23H34O5
Molecular Weight
390.51
Precautions
H302, H315, H319, H335
References & Citations
[1]AGGARWAL, D., et al. A quantitative structure-activity relationship study of 3-hydroxy-3methylglutaryl-coenzyme A reductase inhibitors. Journal of Pharmacobio-Dynamics, 1988;11 (9), 591–599.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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