Propionyl coenzyme A (lithium)

Propionyl coenzyme A lithium, a coenzyme A derivative of propionic acid, is an important metabolic intermediate formed by the thioester bond between coenzyme A and propionic acid. The breakdown and production of Propionyl coenzyme A lithim is important for the metabolism of organisms[1][2].

Product Specifications

CAS Number

[108321-21-7]

UNSPSC

12352204

Hazard Statement

H315, H319, H335

Target

Endogenous Metabolite

Type

Biochemical Assay Reagents

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/propionyl-coenzyme-a-lithium.html

Purity

Solubility

H2O : 50 mg/mL (ultrasonic; warming)

Smiles

CCC(SCCNC(CCNC([C@H](O)C(C)(C)COP(OP(OC[C@@H]1[C@@H](OP(O)(O)=O)[C@@H](O)[C@]([H])(N2C=NC3=C(N)N=CN=C32)O1)(O)=O)(O)=O)=O)=O)=O.[Li].[x]

Molecular Formula

C24H40N7O17P3S.xLi

Precautions

H315, H319, H335

References & Citations

[1] Ernesto J Muñoz-Elías, et al. Role of the methylcitrate cycle in Mycobacterium tuberculosis metabolism, intracellular growth, and virulence. Mol Microbiol. 2006 Jun;60 (5) :1109-22.|[2]Kerry A Lucas, et al. Peroxisomal metabolism of propionic acid and isobutyric acid in plants. J Biol Chem. 2007 Aug 24;282 (34) :24980-9.|[3]Oleg A Shchelochkov, et al. Propionic Acidemia. 2012 May 17 [updated 2016 Oct 6]. In: Adam MP, Everman DB, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA) : University of Washington, Seattle; 1993–2022.