2-O-Ethyl PAF C-16
Product Specifications
UNSPSC Description
2-O-Ethyl PAF C-16 is a homolog of PAF and a competitive ligand for PAF receptor (Platelet-activating Factor Receptor (PAFR)). 2-O-Ethyl PAF C-16 inhibits the binding of the PAF antagonist WEB 2086 (HY-108634) to the PAF receptor with an IC50 of 21 nM[1].
Target Antigen
Platelet-activating Factor Receptor (PAFR)
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/2-o-ethyl-paf-c-16.html
Solubility
10 mM in DMSO
Smiles
CCCCCCCCCCCCCCCCOC[C@@H](OCC)COP(OCC[N+](C)(C)C)([O-])=O
Molecular Weight
509.70
References & Citations
[1]Aoki Y, et al. A radioreceptor binding assay for platelet-activating factor (PAF) using membranes from CHO cells expressing human PAF receptor. J Immunol Methods. 1995 Oct 26;186(2):225-31.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-134101/2-O-Ethyl-PAF-C-16-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-134101/
Clinical Information
No Development Reported
CAS Number
78858-42-1
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