Fulvine

Fulvine is a pyrrolizidine alkaloid isolated from the seeds of Crotalaria fulva. Fulvine is hepatotoxic and can be used to induce hypertensive pulmonary vascular disease in vivo[1].

Product Specifications

CAS Number

[6029-87-4]

UNSPSC

12352005

Hazard Statement

H301-H373

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/fulvine.html

Solubility

10 mM in DMSO

Smiles

O=C(O[C@]1([H])CCN2[C@]1([H])C(CO3)=CC2)[C@H](C)[C@@](C)(O)[C@H](C)C3=O

Molecular Formula

C16H23NO5

Molecular Weight

309.36

Precautions

P260-P264-P270-P330-P405-P501

References & Citations

[1]J M Kay, et al.Fulvine and the pulmonary circulation. Thorax|[2]Schoental R. Rat lung lesions due to Fulvine. J Pathol Bacteriol. 1966 Apr;91 (2) :629-31. |[3]BARNES JM, et al. LESIONS IN THE LUNGS AND LIVERS OF RATS POISONED WITH THE PYRROLIZIDINE ALKALOID Fulvine AND ITS N-OXIDE. J Pathol Bacteriol. 1964 Oct;88:521-31.