MTL-CEBPA

MTL-CEPBA is a small activating RNA targeting for upregulation of C/EBPα. MTL-CEPBA has anti-inflammatory and anti-cancer activity[1].

Product Specifications

CAS Number

[2862057-05-2]

Product Name Alternative

CEBPA-51

UNSPSC

12352208

Target

MicroRNA

Type

Oligonucleotides

Related Pathways

Epigenetics

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/mtl-cebpa.html

Purity

95.52

Solubility

10 mM in H2O

Smiles

[MTL-CEBPA]

Molecular Weight

13464.27

References & Citations

[1]Jiehua Zhou, et al. Anti-inflammatory Activity of MTL-CEBPA, a Small Activating RNA Drug, in LPS-Stimulated Monocytes and Humanized Mice. Mol Ther. 2019 May 8;27 (5) :999-1016.|[2]Reebye V, Huang KW, Lin V, et al. Gene activation of CEBPA using saRNA: preclinical studies of the first in human saRNA drug candidate for liver cancer. Oncogene. 2018;37 (24) :3216-3228. |[3]Combination therapies comprising C/EBPα-targeted short-activating RNA (saRNA) . WO2022229644A1