L-NABE

L-NABE is a nitric oxide (NO) synthase inhibitor. L-NABE is also a potent endothelium dependent vasoconstrictor and inhibitor of relaxation[1][2].

Product Specifications

CAS Number

[7672-27-7]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

NO Synthase

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/l-nabe.html

Solubility

10 mM in DMSO

Smiles

N[C@@H](CCCNC(N[N+]([O-])=O)=N)C(OCC1=CC=CC=C1)=O

Molecular Formula

C13H19N5O4

Molecular Weight

309.32

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Nossaman BD, et al. Nomega-Nitro-L-Arginine Benzyl Ester Enhances Pulmonary Vasopressor Responses to Hypoxia and to Angiotensin II. Am J Ther. 1995 Jul;2 (7) :462-468. |[2]G Thomas, et al. NW-nitro L-arginine benzyl ester, a potent irreversible inhibitor of endothelium dependent relaxation. Biochem Biophys Res Commun. 1991 Sep 30;179 (3) :1677-82.