N-(Azido-PEG3)-N-Boc-PEG4-acid
Product Specifications
UNSPSC Description
N-(Azido-PEG3)-N-Boc-PEG4-acid is a PEG-based PROTAC linker with a terminal azide group and is used in the synthesis of PROTACs[1] N-(Azido-PEG3)-N-Boc-PEG4-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Target Antigen
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-azido-peg3-n-boc-peg4-acid.html
Solubility
10 mM in DMSO
Smiles
O=C(OC(C)(C)C)N(CCOCCOCCOCCN=[N+]=[N-])CCOCCOCCOCCOCCC(O)=O
Molecular Weight
566.64
References & Citations
[1]Kanazaki K, et al. Feasibility of poly(ethylene glycol) derivatives as diagnostic drug carriers for tumor imaging. J Control Release. 2016 Mar 28;226:115-23.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-130598/N-Azido-PEG3-N-Boc-PEG4-acid-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-130598/
Clinical Information
No Development Reported
CAS Number
2112731-95-8
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