Propargyl-PEG6-NHS ester
Product Specifications
UNSPSC Description
Propargyl-PEG6-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG6-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG6-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Target Antigen
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related;PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/propargyl-peg5-c2-nhs-ester.html
Solubility
10 mM in DMSO
Smiles
C#CCOCCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O
Molecular Weight
445.46
References & Citations
[1]Anandan Palani, et al. Insulin-incretin conjugates. WO2017160669A1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-130385/Propargyl-PEG6-NHS-ester-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-130385/
Clinical Information
No Development Reported
CAS Number
2093153-99-0
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
