11β-Prostaglandin E2

11β-Prostaglandin E2 (11β-Dinoprostone), a Prostanoid derivative, inhibits [3H]PGE2 binding to hypothalamic membranes in the rat with a Ki of 53.3 nM[1].

Product Specifications

CAS Number

[38310-90-6]

Product Name Alternative

11β-Dinoprostone; 11β-PGE2

UNSPSC

12352211

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/11β-prostaglandin-e2.html

Concentration

14.18 mM * 200 μL in Methyl acetate

Purity

99.0

Solubility

10 mM in DMSO

Smiles

CCCCC[C@H](O)/C=C/[C@@H]1[C@H](C(C[C@@H]1O)=O)C/C=C\CCCC(O)=O

Molecular Formula

C20H32O5

Molecular Weight

352.47

References & Citations

[1]F Dray, M Heaulme, et al. Prostaglandins of the E series inhibit release of noradrenaline in rat hypothalamus by a mechanism unrelated to classical alpha 2 adrenergic presynaptic inhibition. Neuropharmacology. 1984 Apr;23 (4) :457-62.