Ferulenol

Ferulenol, a sesquiterpene prenylated coumarin derivative, specifically inhibits succinate ubiquinone reductase at the level of the ubiquinonecycle. Ferulenol shows good antimycobacterial activity and haemorrhagic action[1][2][3].

Product Specifications

CAS Number

[6805-34-1]

UNSPSC

12352005

Target

Mitochondrial Metabolism; Oxidative Phosphorylation

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ferulenol.html

Purity

99.0

Solubility

Ethanol : ≥ 50 mg/mL

Smiles

O=C1C(C/C=C(C)/CC/C=C(C)/CC/C=C(C)\C)=C(O)C2=CC=CC=C2O1

Molecular Formula

C24H30O3

Molecular Weight

366.49

References & Citations

[1]Lahouel M, et al. Ferulenol specifically inhibits succinate ubiquinone reductase at the level of the ubiquinonecycle. Biochem Biophys Res Commun. 2007 Mar 30;355 (1) :252-7.|[2]Mamoci E, et al. Chemical composition and in vitro activity of plant extracts from Ferula communis and Dittrichia viscosa against postharvest fungi. Molecules. 2011 Mar 22;16 (3) :2609-25.|[3]DrissLamnaouer, et al. Ferulenol and ω-hydroxyferulenol, toxic coumarins from Ferula communis var. genuine. Volume 26, Issue 6, 1987, Pages 1613-1615.