N-Desethyl amodiaquine-d5
Product Specifications
UNSPSC Description
N-Desethyl amodiaquine-d5 is the deuterium labeled N-Desethyl amodiaquine. N-Desethyl amodiaquine is the major biologically active metabolite of Amodiaquine. N-Desethyl amodiaquine is an antiparasitic agent. IC50 values for strains V1/S and 3D7 are 97 nM and 25 nM, respectively[1].
Target Antigen
Isotope-Labeled Compounds; Parasite
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection;Others
Field of Research
Infection
Purity
99.60
Solubility
10 mM in DMSO
Smiles
ClC(C=C1)=CC2=C1C(NC3=CC(CNC([2H])([2H])C([2H])([2H])[2H])=C(C=C3)O)=CC=N2
Molecular Weight
332.84
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Sasi P, et al. In vivo and in vitro efficacy of amodiaquine against Plasmodium falciparum in an area of continued use of 4-aminoquinolines in East Africa. J Infect Dis. 2009 Jun 1;199(11):1575-82.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Clinical Information
No Development Reported
CAS Number
1173023-19-2
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
