LL320
LL320 is a selective NNMT inhibitor with a Ki, app of 6.8 nM. LL320 exhibits interactions with RNMT, DPH5, and SAHH[1].
Product Specifications
CAS Number
[2672496-32-9]
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ll320.html
Purity
99.91
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O[C@@H]1[C@H](O)[C@@H](CN(CC#CC2=CC=CC(C(N)=O)=C2)CC[C@H](N)C(O)=O)O[C@H]1N3C(N=CN=C4N)=C4N=C3
Molecular Formula
C24H28N8O6
Molecular Weight
524.53
References & Citations
[1]Meng Y, et al. Comparative Analysis of Two NNMT Bisubstrate Inhibitors through Chemoproteomic Studies: Uncovering the Role of Unconventional SAM Analogue Moiety for Improved Selectivity. ACS Chem Biol. 2024 Jan 5.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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