Arochlor 1254

Arochlor 1254 is a polychlorinated biphenyl (PCB) mixture with biphenyl and 54% chlorine. Aroclor 1254 reduced cell viability and induced overproduction of intracellular reactive oxygen species in a dose-dependent manner. Arochlor 1254 exposure reduces calcium homeostasis, osteoblast differentiation and bone formation[1].

Product Specifications

CAS Number

[11097-69-1]

UNSPSC

12352005

Hazard Statement

H302, H373, H410

Target

Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/arochlor-1254.html

Concentration

83.33 μg/mL * 1.2 mL in Methanol

Solubility

10 mM in DMSO

Smiles

[Arochlor1254]

Precautions

H302, H373, H410

References & Citations

[1]R D Kimbrough, et al. Morphological changes in livers of rats fed polychlorinated biphenyls: light microscopy and ultrastructure. Arch Environ Health. 1972 Nov;25 (5) :354-64.