ECF309
ECF309 is a potent and highly selective mTOR inhibitor with an IC50 of 15 nM. eCF309 displays higher selectivity over PI3Ks. eCF309 can be used for the study of breast cancer and prostate cancer[1].
Product Specifications
CAS Number
[2001571-40-8]
UNSPSC
12352005
Target
MTOR
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ecf309.html
Purity
98.2
Solubility
DMSO : 1 mg/mL (ultrasonic; warming)
Smiles
NC1=C2C(N(CC(OCC)OCC)N=C2C3=CC=C(OC(N)=N4)C4=C3)=NC=N1
Molecular Formula
C18H21N7O3
Molecular Weight
383.40
References & Citations
[1]Craig Fraser, et al. eCF309: a potent, selective and cell-permeable mTOR inhibitor. Med. Chem. Commun., 2016, 7, 471-477.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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