Jesaconitine

Jesaconitine is a toxic alkaloid. Jesaconitine can be derived from Aconitum. Jesaconitine is one of the major metabolites that can be detected in the blood of the right atrium after aconitum poisoning. Various types of arrhythimia are characteristic in aconitine intoxication[1].

Product Specifications

CAS Number

[16298-90-1]

UNSPSC

12352005

Target

Drug Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/jesaconitine.html

Solubility

10 mM in DMSO

Smiles

CO[C@@H]1C23[C@@]4([H])[C@](COC)(CN(CC)C2C([C@]5(OC(C)=O)[C@]6([H])[C@@]3([H])C[C@](O)([C@@H](OC)[C@@H]5O)[C@@H]6OC(C7=CC=C(OC)C=C7)=O)[C@@H]4OC)[C@H](O)C1

Molecular Formula

C35H49NO12

Molecular Weight

675.76

References & Citations

[1]Natori Y, et al. A simple and rapid method for quantifying aconitines and their metabolites in whole blood by modified QuEChERS and liquid chromatography/tandem mass spectrometry (LC/MS/MS) . Forensic Sci Int. 2022 Dec;341:111475.