SKOG102
SKOG102 is a potent OLIG2 inhibitor that is directly engaging OLIG2 and interferes with the ability of OLIG2 to bind DNA. SKOG102 can be used for the research of glioblastoma (GBM) [1].
Product Specifications
CAS Number
[21062-28-2]
UNSPSC
12352005
Target
OLIG2
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/skog102.html
Purity
99.09
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
N=C(NC1=NC(C)=CC(NC2CN(CC)CCC2)=N1)NC3=CC=C(Cl)C(Cl)=C3
Molecular Formula
C19H25Cl2N7
Molecular Weight
422.35
References & Citations
[1]Tsigelny IF, et, al. Multiple spatially related pharmacophores define small molecule inhibitors of OLIG2 in glioblastoma. Oncotarget. 2017 Apr 4;8 (14) :22370-22384.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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