Ro 41-0960
Product Specifications
UNSPSC Description
Ro 41-0960 is a selective catechol-O-methyltransferase(COMT) inhibitor[1].
Target Antigen
COMT
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ro-41-0960.html
Purity
98.0
Solubility
DMSO : 20 mg/mL (ultrasonic;warming)
Smiles
O=C(C1=CC([N+]([O-])=O)=C(C(O)=C1)O)C2=CC=CC=C2F
Molecular Weight
277.20
References & Citations
[1]Storch A, et al. Catechol-O-methyltransferase inhibition attenuates levodopa toxicity in mesencephalic dopamine neurons. Mol Pharmacol. 2000 Mar;57(3):589-94.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-125339/Ro-41-0960-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-125339/Ro-41-0960-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
125628-97-9
Curated Selection
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