Amidepsine A

Amidepsine A is a fungal metabolite isolated from the culture broth of Humicola sp. FO-2942 that inhibits Diacylglycerol acyltransferases (DGAT) activity[1].

Product Specifications

CAS Number

[169181-28-6]

UNSPSC

12352005

Hazard Statement

H302+H312+H332

Target

Acyltransferase

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/amidepsine-a.html

Purity

98.38

Solubility

DMSO : 5.79 mg/mL (ultrasonic; warming)

Smiles

O=C(OC1=CC(C)=C(C(OC2=CC(C)=C(C(NC(C(O)=O)C)=O)C(O)=C2)=O)C(O)=C1)C3=C(C)C=C(OC)C=C3OC

Molecular Formula

C29H29NO11

Molecular Weight

567.54

Precautions

H302+H312+H332

References & Citations

[1]Tomoda H, et al. Amidepsines, inhibitors of diacylglycerol acyltransferase produced by Humicola sp. FO-2942. I. Production, isolation and biological properties. J Antibiot (Tokyo) . 1995 Sep;48 (9) :937-41.