Quinalizarin

Quinalizarin is a potent, selective and cell-permeable protein kinase CK2 inhibitor with an Ki of ~50 nM and an IC50 of 110 nM. Quinalizarin can induce apoptosis of certain cancer cells[1].

Product Specifications

CAS Number

[81-61-8]

UNSPSC

12352005

Hazard Statement

H302, H410

Target

Casein Kinase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Stem Cell/Wnt

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/quinalizarin.html

Purity

97.1

Solubility

DMSO : 10 mg/mL (ultrasonic; warming)

Smiles

O=C1C2=C(C(O)=CC=C2O)C(C3=CC=C(O)C(O)=C13)=O

Molecular Formula

C14H8O6

Molecular Weight

272.21

Precautions

H302, H410

References & Citations

[1]Cozza G, et al. Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2. Biochem J. 2009;421 (3) :387-395. Published 2009 Jul 15.