Runx1-CBFβ interaction inhibitor 1
Product Specifications
UNSPSC Description
Runx1-CBFβ interaction inhibitor 1 is an allosteric inhibitior of Runt domain-CBFb interaction (IC50=3.2 μM)[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/runx1-cbfβ-interaction-inhibitor-1.html
Solubility
10 mM in DMSO
Smiles
COC(C=C1)=CC=C1C2=C(CC)SC(N)=N2
Molecular Weight
234.32
References & Citations
[1]Michael J Gorczynski, et al. Allosteric inhibition of the protein-protein interaction between the leukemia-associated proteins Runx1 and CBFbeta. Chem Biol. 2007 Oct;14(10):1186-97.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-124137/Runx1-CBFβ-interaction-inhibitor-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-124137/
Clinical Information
No Development Reported
CAS Number
493028-20-9
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