Aminooxy-PEG4-alcohol
Product Specifications
UNSPSC Description
Aminooxy-PEG4-alcohol is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Aminooxy-PEG4-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].
Target Antigen
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related;PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/aminooxy-peg4-alcohol.html
Solubility
10 mM in DMSO
Smiles
NOCCOCCOCCOCCO
Molecular Weight
209.24
References & Citations
[1]Heather D. Maynard, et al. Method of creating hydrogels through oxime bond formation. US20150202305A1.|[2]Murray BS, et al. Reactive thermoresponsive copolymer scaffolds. Chem Commun (Camb). 2010 Dec 7;46(45):8651-3.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-124123/Aminooxy-PEG4-alcohol-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-124123/
Clinical Information
No Development Reported
CAS Number
106492-60-8
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