RX 67668

RX 67668 is a potent cholinesterase inhibitor with an IC50 of 5 μM for both acetylcholinesterase (AChE) and butyrylcholinesterase. RX 67668 can reverse the neuromuscular blockade induced by D-tubocurarine. RX 67668 is a muscle relaxant used to relieve skeletal muscle fatigue[1][2].

Product Specifications

CAS Number

[40709-76-0]

UNSPSC

12352005

Target

Cholinesterase (ChE)

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/rx-67668.html

Solubility

10 mM in DMSO

Smiles

[H]Cl.N1([C@H]2[C@@H](C3=CC=CC=C3)CCCC2)CCCC1

Molecular Formula

C16H24ClN

Molecular Weight

265.82

References & Citations

[1]Doxey JC, et al. Some pharmacological properties of RX 67668--a new anticholinesterase. Br J Pharmacol. 1972 Nov;46 (3) :568P-569P.|[2]Metcalf G, wt al. Evaluation of RX 72601 as an anti-curare agent. Br J Anaesth. 1975 Apr;47 (4) :451-6.