Streptochlorin

Streptochlorin (SF2583A) is an antibiotic. Streptochlorin has antitrypanosomal activity with an IC50 value of 230 ng/ml for GUTat 3.1[1][2].

Product Specifications

CAS Number

[120191-51-7]

Product Name Alternative

SF2583A

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Antibiotic; Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/streptochlorin.html

Solubility

10 mM in DMSO

Smiles

ClC1=C(C2=CNC3=C2C=CC=C3)OC=N1

Molecular Formula

C11H7ClN2O

Molecular Weight

218.64

Precautions

H315, H319

References & Citations

[1]Shin DY, et, al. Streptochlorin isolated from Streptomyces sp. Induces apoptosis in human hepatocarcinoma cells through a reactive oxygen species-mediated mitochondrial pathway. J Microbiol Biotechnol. 2008 Nov;18 (11) :1862-8.|[2]Iwatsuki M, et, al. In vitro antitrypanosomal activity of 12 low-molecular-weight antibiotics and observations of structure/activity relationships. J Antibiot (Tokyo) . 2010 Oct;63 (10) :619-22.