Streptochlorin
Streptochlorin (SF2583A) is an antibiotic. Streptochlorin has antitrypanosomal activity with an IC50 value of 230 ng/ml for GUTat 3.1[1][2].
Product Specifications
CAS Number
[120191-51-7]
Product Name Alternative
SF2583A
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Antibiotic; Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/streptochlorin.html
Solubility
10 mM in DMSO
Smiles
ClC1=C(C2=CNC3=C2C=CC=C3)OC=N1
Molecular Formula
C11H7ClN2O
Molecular Weight
218.64
Precautions
H315, H319
References & Citations
[1]Shin DY, et, al. Streptochlorin isolated from Streptomyces sp. Induces apoptosis in human hepatocarcinoma cells through a reactive oxygen species-mediated mitochondrial pathway. J Microbiol Biotechnol. 2008 Nov;18 (11) :1862-8.|[2]Iwatsuki M, et, al. In vitro antitrypanosomal activity of 12 low-molecular-weight antibiotics and observations of structure/activity relationships. J Antibiot (Tokyo) . 2010 Oct;63 (10) :619-22.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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