Aranciamycin
Aranciamycin (Compound 1) is an anthracycline antibiotic with collagenase inhibitory activity (IC503.7*10-7M) . Aranciamycin can be used to inhibit DNA synthesis in tumor cells [1].
Product Specifications
CAS Number
[72389-06-1]
UNSPSC
12352005
Hazard Statement
H301, H312, H330, H410
Target
Antibiotic
Type
Natural Products
Related Pathways
Anti-infection
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/aranciamycin.html
Solubility
10 mM in DMSO
Smiles
O=C1[C@@](C)(O)[C@@H](OC)[C@H](O[C@H]2[C@@H]([C@@H]([C@H]([C@H](C)O2)O)O)OC)C(C(O)=C3C(C4=C5C=CC=C4O)=O)=C1C=C3C5=O
Molecular Formula
C27H28O12
Molecular Weight
544.50
Precautions
H301, H312, H330, H410
References & Citations
[1]Bols M, et al. Inhibition of collagenase by aranciamycin and aranciamycin derivatives. J Med Chem. 1992 Jul 24;35 (15) :2768-71.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
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