MDL 27399
MDL 27399 is an inhibitor of human neutrophil cathepsin G (Ki = 7 μM) . MDL 27399 can be used for research of inflammatory diseases[1].
Product Specifications
CAS Number
[131374-22-6]
UNSPSC
12352005
Target
Cathepsin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/mdl-27399.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](NC([C@H]1N(CCC1)C([C@@H](NC([C@@H](NC(CCC(OC)=O)=O)C)=O)C)=O)=O)CC2=CC=CC=C2)OC
Molecular Formula
C26H36N4O8
Molecular Weight
532.59
References & Citations
[1]N.S. Doherty, et al. Novel inhibitors of polymorphonuclear neutrophil (PMN) elastase and cathepsin G: Evaluation in vitro of their potential for the treatment of inflammatory connective tissue damage. International Journal of Immunopharmacology. Volume 12, Issue 7, 1990, Pages 787-795
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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