BMS-903452
Product Specifications
UNSPSC Description
BMS-903452 is a potent and selective GPR119 agonist for diabetes research[1].
Target Antigen
GPR119
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/bms-903452.html
Solubility
10 mM in DMSO
Smiles
ClC1=CN=C(N2CCC(OC3=CC(N(C4=CC=C(S(=O)(C)=O)C=C4F)C=C3Cl)=O)CC2)N=C1
Molecular Weight
513.37
References & Citations
[1]Wacker DA, et al. Discovery of 5-chloro-4-((1-(5-chloropyrimidin-2-yl)piperidin-4-yl)oxy)-1-(2-fluoro-4-(methylsulfonyl)phenyl)pyridin-2(1H)-one (BMS-903452), an antidiabetic clinical candidate targeting GPR119. J Med Chem. 2014 Sep 25;57(18):7499-508.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-12375/BMS-903452-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-12375/
Clinical Information
Phase 1
CAS Number
1339944-47-6
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