Nybomycin

Nybomycin, an antibiotic, exhibits antiphage and antibacterial properties. Nybomycin binds to DNA and induces a unique morphological change to mycobacterial bacilli leading the bacterial cell death[1][2].

Product Specifications

CAS Number

[30408-30-1]

UNSPSC

12352005

Target

Antibiotic; Bacterial

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/nybomycin.html

Purity

99.0

Solubility

Acetic acid : 15 mg/mL (ultrasonic; warming)

Smiles

O=C1N2C3=C(C4=C(C=C3C(C)=C1)C(CO)=CC(N4C)=O)OC2

Molecular Formula

C16H14N2O4

Molecular Weight

298.29

References & Citations

[1]Strelitz F, et, al. NYBOMYCIN, A NEW ANTIBIOTIC WITH ANTIPHAGE AND ANTIBACTERIAL PROPERTIES. Proc Natl Acad Sci U S A. 1955 Sep 15;41 (9) :620-4.|[2]Arai M, et, al. Anti-dormant mycobacterial activity and target analysis of nybomycin produced by a marine-derived Streptomyces sp. Bioorg Med Chem. 2015 Jul 1;23 (13) :3534-41.