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Fotagliptin

Product Specifications

UNSPSC Description

Fotagliptin is a Dipeptidyl Peptidase IV (DPP-4) inhibitor (IC50=2.27 nM). Fotagliptin displays great security in rat and dog. Fotagliptin can be used for Type 2 diabetes mellitus research[1].

Target Antigen

Dipeptidyl Peptidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/fotagliptin.html

Solubility

10 mM in DMSO

Smiles

CC(C1=O)=NN=C(N2C[C@@H](CCC2)N)N1CC3=C(C=CC(F)=C3)C#N

Molecular Weight

342.37

References & Citations

[1]Wang Z, et al. Development and validation of a UPLC-MS/MS method for simultaneous determination of fotagliptin and its two major metabolites in human plasma and urine. Bioanalysis. 2017 Feb;9(4):381-393.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-123377/Fotagliptin-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-123377/

Clinical Information

Phase 3

CAS Number

1312954-58-7

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