Fexarine
Fexarine is a potent, non-steroidal and selective agonist of farnesoid X receptor (EC50: 38 nM) . Fexarine can be used for the research of diseases linked to cholesterol, bile acids[1].
Product Specifications
CAS Number
[574013-67-5]
UNSPSC
12352005
Target
FXR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/fexarine.html
Solubility
10 mM in DMSO
Smiles
O=C(/C=C/C1=CC=CC(N(C(C2CCCCC2)=O)CC3=CC=C(C=C3)C4=CC=C5OCOC5=C4)=C1)OC
Molecular Formula
C31H31NO5
Molecular Weight
497.58
References & Citations
[1]Michael R. Downes, et al. Non-steroidal farnesoid X receptor modulators and methods for the use thereof. Patent US7671085 B2.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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