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JNJ-40255293

Product Specifications

UNSPSC Description

JNJ-40255293 is a high-affinity human A 2A receptor antagonist with a KiKi of 7.5 nM. JNJ-40255293 can be used in the research of neurodegenerative diseases such as Parkinson's disease[1].

Target Antigen

Adenosine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/jnj-40255293.html

Solubility

10 mM in DMSO

Smiles

O=C1C2=C(C=C(C=C2)OCCN3CCOCC3)C4=NC(N)=NC(C5=CC=CC=C5)=C41

Molecular Weight

402.45

References & Citations

[1]John R Atack, et al. JNJ-40255293, a novel adenosine A2A/A1 antagonist with efficacy in preclinical models of Parkinson's disease. ACS Chem Neurosci. 2014 Oct 15;5(10):1005-19.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-122105/JNJ-40255293-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-122105/

Clinical Information

No Development Reported

CAS Number

1147271-25-7

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