Lavoltidine
Product Specifications
UNSPSC Description
Lavoltidine (Loxtidine) is an an orally active, irreversible and highly potent histamine H2-receptor antagonist. Lavoltidine strongly inhibits gastric acid secretion and also induces hypergastrinemia[1].
Target Antigen
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lavoltidine.html
Solubility
10 mM in DMSO
Smiles
OCC1=NN(C(NCCCOC2=CC=CC(CN3CCCCC3)=C2)=N1)C
Molecular Weight
359.47
References & Citations
[1]Takaishi S, et al. Synergistic inhibitory effects of gastrin and histamine receptor antagonists on Helicobacter-induced gastric cancer.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-121450/Lavoltidine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-121450/
Clinical Information
Phase 2
CAS Number
76956-02-0
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