Dipivefrin

Dipivefrin is a potent adrenergic agonist. Dipivefrin is an adrenergic pro-agent. Dipivefrin can be used for reduce IOP (intraocular pressure) in patients suffering from chronic open angle glaucoma[1][2].

Product Specifications

CAS Number

[52365-63-6]

UNSPSC

12352005

Hazard Statement

H315-H319-H320

Target

Adrenergic Receptor; Endogenous Metabolite

Type

Reference compound

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/dipivefrin.html

Solubility

10 mM in DMSO

Smiles

CC(C)(C(OC1=CC=C(C=C1OC(C(C)(C)C)=O)C(CNC)O)=O)C

Molecular Formula

C19H29NO5

Molecular Weight

351.44

Precautions

P264-P280-P302+P352-P305+P351+P338-P362

References & Citations

[1]Kass MA, et al. Dipivefrin and epinephrine treatment of elevated intraocular pressure: a comparative study. Arch Ophthalmol. 1979 Oct;97 (10) :1865-6.|[2]Alkholief M, et al. Thermoresponsive sol-gel improves ocular bioavailability of Dipivefrin hydrochloride and potentially reduces the elevated intraocular pressure in vivo. Saudi Pharm J. 2020 Aug;28 (8) :1019-1029.