HX600

HX600 is a synthetic agonist for RXR (Retinoid X Receptor) heterodimer complex. HX600 prevents ischemia-induced neuronal damage. HX600 has orally bioactivity[1].

Product Specifications

CAS Number

[172705-89-4]

UNSPSC

12352005

Target

RAR/RXR

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/hx600.html

Purity

99.40

Solubility

10 mM in DMSO

Smiles

O=C(O)C1=CC=C(C2=NC3=CC=CC=C3N(C)C4=CC5=C(C(C)(C)CCC5(C)C)C=C42)C=C1

Molecular Formula

C29H30N2O2

Molecular Weight

438.56

References & Citations

[1]Siddhesh S Kamat, et al. Immunomodulatory lysophosphatidylserines are regulated by ABHD16A and ABHD12 interplay. Nat Chem Biol 2015 Feb;11 (2) :164-71.|[2]Hiroki Umemiya, et al. Action Mechanism of Retinoid-Synergistic Dibenzodiazepines. Biochem Biophys Res Commun. 1997 Apr 7;233 (1) :121-5.