17(R)-HDHA
Product Specifications
UNSPSC Description
17(R)-HDHA (17(R)-HDoHE) is a pro-resolving mediator (SPM). 17(R)-HDHA enhances the differentiation of B cells toward the CD27(+)CD38(+) antibody-secreting cell phenotype, thereby strongly increasing IgM and IgG production by activated B cells. 17(R)-HDHA does not affect cell proliferation and is non-toxic to cells[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/17-r-hdha.html
Solubility
10 mM in DMSO
Smiles
CC/C=C\C[C@@H](O)/C=C/C=C\C/C=C\C/C=C\C/C=C\CCC(O)=O
Molecular Weight
344.49
References & Citations
[1]Ramon S, et al. Specialized proresolving mediators enhance human B cell differentiation to antibody-secreting cells. J Immunol. 2012 Jul 15;189(2):1036-42.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-120255/17-R-HDHA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-120255/
Clinical Information
No Development Reported
CAS Number
155976-53-7
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