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CC618

CC618 is a selective peroxisome proliferator-activated receptor (PPARβ/δ) antagonist that exhibits antagonism by covalently binding to PPARβ/δ receptors[1].

Product Specifications

CAS Number

[1680204-90-3]

UNSPSC

12352005

Target

PPAR

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/cc618.html

Purity

99.94

Solubility

DMSO : ≥ 25 mg/mL

Smiles

O=C(NCCS(=O)(C1=NC=C(C=C1)C(F)(F)F)=O)C2=C(N=C(S2)C3=CC=C(C=C3)C(F)(F)F)C

Molecular Formula

C20H15F6N3O3S2

Molecular Weight

523.47

References & Citations

[1]Kaupang Å, et al. Synthesis, biological evaluation and molecular modeling studies of the PPARβ/δ antagonist CC618. Eur J Med Chem. 2015 Apr 13;94:229-36.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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