CC618
CC618 is a selective peroxisome proliferator-activated receptor (PPARβ/δ) antagonist that exhibits antagonism by covalently binding to PPARβ/δ receptors[1].
Product Specifications
CAS Number
[1680204-90-3]
UNSPSC
12352005
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/cc618.html
Purity
99.94
Solubility
DMSO : ≥ 25 mg/mL
Smiles
O=C(NCCS(=O)(C1=NC=C(C=C1)C(F)(F)F)=O)C2=C(N=C(S2)C3=CC=C(C=C3)C(F)(F)F)C
Molecular Formula
C20H15F6N3O3S2
Molecular Weight
523.47
References & Citations
[1]Kaupang Å, et al. Synthesis, biological evaluation and molecular modeling studies of the PPARβ/δ antagonist CC618. Eur J Med Chem. 2015 Apr 13;94:229-36.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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