Chloropyramine

Chloropyramine is competitive reversible H1 receptor antagonist. Chloropyramine also has anti-tumour activity in breast cancer. Chloropyramine can be used for the research of allergic conditions, such as conjunctivitis and bronchial asthma[1][2].

Product Specifications

CAS Number

[59-32-5]

UNSPSC

12352005

Hazard Statement

H302

Target

Apoptosis; Histamine Receptor

Type

Reference compound

Related Pathways

Apoptosis; GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Applications

Cancer-programmed cell death

Field of Research

Cancer; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/chloropyramine.html

Solubility

10 mM in DMSO

Smiles

CN(CCN(C1=CC=CC=N1)CC2=CC=C(Cl)C=C2)C

Molecular Formula

C16H20ClN3

Molecular Weight

289.80

Precautions

P264-P270-P330-P501

References & Citations

[1]Joshua T Burgess, et al. SASH1 mediates sensitivity of breast cancer cells to chloropyramine and is associated with prognosis in breast cancer. Oncotarget. 2016 Nov 8;7 (45) :72807-72818.