(E) -Aminoquinol
(E) -Aminoquinol (XIB4035) is a GFRα-1 agonist. (E) -Aminoquinol has mimic neurotrophic effects of GDNF, and induces Ret autophosphorylation in Neuro-2A cells. (E) -Aminoquinol can be used for research of Parkinson’s disease[1].
Product Specifications
CAS Number
[529507-84-4]
Product Name Alternative
XIB4035
UNSPSC
12352005
Hazard Statement
H301, H413
Target
GDNF Receptor
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/e-aminoquinol.html
Purity
99.70
Solubility
DMSO : ≥ 100 mg/mL
Smiles
CCN(CC)CCCC(C)NC1=CC(/C=C/C2=C(C=CC=C2)Cl)=NC3=C1C=CC(Cl)=C3
Molecular Formula
C26H31Cl2N3
Molecular Weight
456.45
Precautions
H301, H413
References & Citations
[1]Tokugawa K, et al. XIB4035, a novel nonpeptidyl small molecule agonist for GFRalpha-1. Neurochem Int. 2003 Jan;42 (1) :81-6.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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