NNGH
NNGH is a stromelysin-1 (MMP-3) inhibitor. MMP-3 is both a direct transcriptional target and a necessary contributor of the Wnt/β-catenin signaling pathway. Matrix metalloproteinases (MMPs) play a well-defined role in later stages of tumor progression[1].
Product Specifications
CAS Number
[161314-17-6]
UNSPSC
12352005
Target
MMP
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nngh.html
Purity
99.6
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
ONC(CN(CC(C)C)S(C1=CC=C(C=C1)OC)(=O)=O)=O
Molecular Formula
C13H20N2O5S
Molecular Weight
316.37
References & Citations
[1]Laurence Blavier, et al. Stromelysin-1 (MMP-3) is a target and a regulator of Wnt1-induced epithelial-mesenchymal transition (EMT) . Cancer Biol Ther. 2010 Jul 15;10 (2) :198-208.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
485629 100 µL
MECR (Trans-2-enoyl-CoA Reductase, Mitochondrial, Mitochondrial Trans-2-enoyl-CoA Reductase)
Ask
View Details 
LS051022-100ug 100 µg
Glutaredoxin 2 (GLRX2) (NM_016066) Human Over-expression Lysate
Ask
View Details