AA-CW236
AA-CW236 is a MGMT (O6-methylguanine DNA methyltransferase) inhibitor. AA-CW236 targets MGMT active site Cys145 for covalent modification[1].
Product Specifications
CAS Number
[1869921-96-9]
UNSPSC
12352005
Target
DNA Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/aa-cw236.html
Purity
99.9
Solubility
DMSO : 25 mg/mL (ultrasonic; warming)
Smiles
FC(F)(F)OC1=CC=C(C2=C(CCl)N(CCC3=C(C)ON=C3C)N=N2)C=C1
Molecular Formula
C17H16ClF3N4O2
Molecular Weight
400.78
References & Citations
MGMT (O6-methylguanine DNA methyltransferase)
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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