MK771
MK771 is a thyrotrophin-releasing hormone analog. MK771 induces blinking and forepaw licking. MK771 has the potential for the research of morphine abstinence syndrome[1][2].
Product Specifications
CAS Number
[66537-55-1]
UNSPSC
12352005
Target
Thyroid Hormone Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mk771.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@H](C(N1CSC[C@@H]1C(N)=O)=O)CC2=CNC=N2)[C@@H](N3)CCCC3=O
Molecular Formula
C16H22N6O4S
Molecular Weight
394.45
References & Citations
[1]McCreary AC, et al. The thyrotrophin-releasing hormone analogue MK771 induces tic-like behaviours: the effects of dopamine D1 and D2 receptor antagonists. Eur J Pharmacol. 1999 Mar 12;369 (1) :1-9.|[2]Bhargava HN, et al. Comparative effects of thyrotropin releasing hormone, MK-771 and DN-1417 on morphine abstinence syndrome. Psychopharmacology (Berl) . 1985;87 (2) :141-6.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-119174/MK771-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-119174/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
OAAF00396-100UG-FITC 100 µg
ZAP70 Antibody (Phospho-Tyr493) : FITC (OAAF00396-FITC)
Ask
View Details 49552124 3 x 1.0μg DNA
Vmn1r137 CRISPRa sgRNA lentivector (set of three targets)(Mouse)
Ask
View Details 
307425 1 Pack (1 Panel (s) x 1 Pack)
P/PIC914/NT/ALU-DIA150-1 Prohibited Activity Signs (No Adhesive)
Ask
View Details