AS604872
Product Specifications
UNSPSC Description
AS604872 is an orally active, potent and selective prostaglandin F2α receptor (FP) antagonist with a Ki of 35 nM in humans, 158 nM in rats and 323 nM in mice. AS604872 inhibits contractions and delays labour[1].
Target Antigen
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/as604872.html
Solubility
10 mM in DMSO
Smiles
O=C([C@H]1N(CCS1)S(=O)(C2=CC=C(C3=CC=CC=C3)C=C2)=O)N[C@@H](C4=CC=CC=N4)C5=CC=CC=C5
Molecular Weight
515.65
References & Citations
[1]Rocco Cirillo, et al. Arrest of preterm labor in rat and mouse by an oral and selective nonprostanoid antagonist of the prostaglandin F2alpha receptor (FP). Am J Obstet Gynecol. 2007 Jul;197(1):54.e1-9.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-118388/AS604872-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-118388/
Clinical Information
No Development Reported
CAS Number
612532-48-6
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