Dexchlorpheniramine
Dexchlorpheniramine is an potent and blood-brain barrier (BBB) penetrant histamine 1 (H1) receptor antagonist with anticholinergic properties. Dexchlorpheniramine can be used for researching allergies[1].
Product Specifications
CAS Number
[25523-97-1]
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/dexchlorpheniramine.html
Solubility
10 mM in DMSO
Smiles
CN(CC[C@@H](C1=CC=C(Cl)C=C1)C2=NC=CC=C2)C
Molecular Formula
C16H19ClN2
Molecular Weight
274.79
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]Patkai J, et al. Deleterious effects of IL-9-activated mast cells and neuroprotection by antihistamine drugs in the developing mouse brain. Pediatr Res. 2001 Aug;50 (2) :222-30.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
H1 Receptor
Curated Selection
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