Alyssin

Alyssin, found in Cruciferous Vegetables, exerts anticancer activity in HepG2 by increasing intracellular reactive oxygen species and tubulin depolymerization[1].

Product Specifications

CAS Number

[646-23-1]

UNSPSC

12352211

Hazard Statement

H225-H350

Target

Microtubule/Tubulin; Reactive Oxygen Species (ROS)

Type

Natural Products

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/alyssin.html

Solubility

10 mM in DMSO

Smiles

O=S(C)CCCCCN=C=S

Molecular Formula

C7H13NOS2

Molecular Weight

191.31

Precautions

P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P405-P501

References & Citations

[1]Pocasap P, et al. Alyssin and Iberin in Cruciferous Vegetables Exert Anticancer Activity in HepG2 by Increasing Intracellular Reactive Oxygen Species and Tubulin Depolymerization. Biomol Ther (Seoul) . 2019;27 (6) :540-552.